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KMID : 0869619920090010020
Journal of Korean Society of Hospital Pharmacists
1992 Volume.9 No. 1 p.20 ~ p.26
Evaluation of bactericidal activities of commonly used disinfectants against clinically isolated strains in St. Mary hospital
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Abstract
Considering the increased incidence of hospital-acquired infections, the bactericidal efficacies of commonly used 11 disinfectants in 27 concentrations were examined against 18 strained isolated from patients. Each 0.5§¢ strain broth(1~5¡¿10^(6)/§¢) was mixed with 4.5§¢ disinfectants and plated for bacterial survival at 0.5, 1, 2, 5, 10, 20 and30 min for disinfectants, and 1, 5, 10, 20 and 30 min for antiseptics. As the results, all strains tested were killed within 30 sec in 0.5%, 7.5%, 10% povidone iodine, 0.05%, 0.1% 1% benzalkonium choloride, 0.1%, 0.5% chlorhexidine gluconate and 3% hydrogen peroxide, 3% boric acid and Physol^(¢ç)(1% benzalkonium chloride+surfactants) could not kill all strains even after 30 min of contact. In testing 11 antiseptics, all strains tested were killed within 1 min with 2% glutaral, 0.02%, 0.1%, 1% sodium hypochlorite and 1%, 3% Lysol.
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